秒速赛车控制器

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國內新聞
藥源回顧2019:讓一部分患者先健康起來
發布時間: 2019-12-24     來源: 美中藥源

秒速赛车控制器JIJIANGGUOQUDE2019NIANZHIYAOJIEFASHENGLEBUSHAOYANHUALIAOLUANDESHIQING,JINTIANWOMENJIUHUIGUYIXIAZHEYINIANDEJINZHANYUCUOZHE。ZHIFUBUMENMIANLINJUDAYALI,BUDEBUDUIYIYOUBIAOZHUNLIAOFAHUORENQUNJUDAJIBINGXINYAOTICHUGENGGAOYAOQIU,ERBUFENLINGYUJISHUTUPOLINGYOUXIECHUANTONGWANJIDEZHILIAOCHENGWEIKENENG。ZHELIANGGEGUANJIANYINSUJUEDINGZHIYAOYEXUYAOXIANGJILIGAODUQINGXI、ZUIKENENGYOUGAOJIAZHIQUFENDEJIBINGLINGYUQINGXIE,HUANZHERENSHUCHENGWEICIYAOYINSU。ZHEYUCHUANTONGQINMINDEZHONGBANGYAOWUMOSHIWANQUANBUTONG,XIANZAIDEXINYAOGENGJIAJINGZHUNHUA、GETIHUA、SHECHIHUA。YIBUFENHUANZHEHUIHUOQUJUDASHOUYIXIANJIANKANGQILAI,DANGENGDUOHUANZHEXUYAONAIXINDENGDAI。

1. 大環境:限價壓力空前

YAOPINJIAGEZENGCHANGSUDUDUONIANCHAOGUOTONGZHANGLV,YAOPINKEJIXINGYIJINGCHENGWEIXIANZAIYIGEZHUYAOSHEHUIWENTI。ZHIFUBUMENYUELAIYUEJIANGCHANPINGAOJIAZHIZUOWEIXIANJUETIAOJIAN,DUIYUCHANGJIANDAZHONGBINGYAOWUTAIDUGENGWEIKEKE、CHUFEIJIAZHIFEICHANGXIANZHUFOUZEYONGLIANGTAIDAZHEYITIAOJIULINGZHIFUJIGOUWANGERSHENGWEI。XIAOFEIZHEZIRANYUANSHENGZAIDAO,MINCEZHONGZHIYAOYESHENGYUZAISUOYOUXINGYEZHONGDIANDI。ZHENGZHIJIAMENZEDUIYAOCHANGKOUZHUBIFA,ZHIBINGJIURENDEXINGYEBEICHENGZUOSHARENFAN。NIANCHUTELANGPUZONGTONGWEIXIEYUNXUCONGHAIWAIJINKOULIANJIAYAOWU,NIANDIMINZHUDANGTONGGUOHR3FAAN、RUGUOLIFAJIANGDADAJIANGDIXINYAOCHANCHUSHULIANG。YAOJIASHIGEFUZAWENTI,HESUOYOUFUZAWENTIYIYANGMEIGERENDOUYOUGEJIANDANJIEJUEBANFA。ZAICIZHONGYAZHIXIA, YAOCHANGYIFANGMIANCHENGNUOMEINIANZHANGJIABUCHAOGUO10%、LINGYIFANGMIANBEIPOZHONGXINBUJUZHUGONGFANGXIANGHEKAIFAXIANGYINGXINJISHU。

2. 適應癥:讓一部分患者先健康起來

ZHONGGUOGAIGEKAIFANGZHICHUBAIFEIDAIXING,GUOJIATICHURANGYIBUFENRENXIANFUQILAIDEZHANLVEFANGZHEN,XIANZAIZHIYAOYEMIANLINLEISIXUANZE。ZHIFUBUMENLUNLISHANGBUNENGXUANZENAXIEJIBINGYOUYOUXIANQUAN,DANYAOQIUXINYAOSUOJIABIXUYUJIAZHIGUAGOU。ZHEZAISHISHISHANGBAYOUXIANQUANGEILEJILIQINGCHU、BINGLIDANYI、QUESHAOYUBIAOZHUNLIAOFA、DUIDUFUZUOYONGJIAOKUANRONGDEHANJIANBING。CHANGJIANDAZHONGBINGYAOWUBUJINJISHUSHANGNANYIXIANSHITUCHUJIAZHI,ZHENGMINGZHEGEJIAZHIYEXUYAODALIANG、GAOFENGXIANTOUREN,ZHUJIANCHENGWEIHANJIANTOUZILINGYU。

2.1. 慢性病

秒速赛车控制器ANJIBINGFUDANKANXIFANGZHUYAOSHICHANGDEZUIZHUYAOZHISIYINSUSHIXINXUEGUAN、ZHONGLIU、HELAONIANTUIXINGJIBING,QIZHONGZHIYOUZHONGLIULINGYUJILEILEZUGOUKEXUEZHISHIXIFENCHENGDUOZHONGZAIFENZISHUIPINGXIANGDUIDANYI、KEYIGEGEJIPODEJIBING,YINCICHENGWEIXIANZAIZHIYAOYETOUZIQIANGDUZUIDA、XINJISHUFAZHANZUIKUAIDELINGYU。ZHEGEWOMENHOUMIANXIANGXIJIANGYIXIA。

XINXUEGUANJIBINGJINGUANMEIYOUZUGOUDEFENZISHUIPINGLIJIE,DANXUEYA、XUETANG、XUEZHIYUCVDGUANXIXIANGDUIQINGCHU。JIANJIEJIANGDIXINXUEGUANJIBINGFENGXIANSUIRANNANDUHENDA、DANYINYAOWUDEGUANGPUXINGRENGYOUBUXIAOXIYINLI。JINNIANZUIZHONGYAOJINZHANYAOSUANPCSK9 RNAiYAOWUinclisiranXIANSHICHANGQILIAOXIAO、ANQUANXING、HESHIYONGFANGBIANXING,NUOHUAYINCICHIZI97YISHOUGOUMedicines Company。LINGYIGEZHONGYAOJINZHANSHISGLT2YIZHIJIJIXUXIANSHIGUANGPUHUOXINGRUXINSHUAI、CKDLIAOXIAODENG。NUOHENUODEDEKOUFUGLPJIDONGJISUOMALUTAISHANGSHI、AmarinCHUNYUYOUZHIJIVascepaDEKUOZHANBIAOQIANYESHIZHONGYAOSHIJIANDANDOUSHIYILIAOZHIZHONGDESHIQING。MANXINGBINGYAOWUKAIFANANDUYESHILINGRENSHENGWEI,DUOGECENGBEIKANHAODEYAOWUYUEZUOCHUANGKOUYUEXIAO、SHANGYEQIANJINGKANYOU。RULILAILEIGLP/GCPSHOUTISHUANGJIDONGJISUIRANERQILIAOXIAOBUCUODANANQUANJILIANGCHUANGKOUFEICHANGXIAO、SHIFOUNENGWEIXIEGLPNANYIYUCE,YANGSENZHIYAOZEJIANGLEISIYAOWUHM12525ATUIHUANGEIHEZUOHUOBANHANMEI。WANJIHFpEFJITUIRUOGANYAOWUBAOKUOEntrestoDETIAOZHAN,YIRANTIANXIAWUDI。12YUE,CHUANTONGXINXUEGUAN、TANGNIAOBINGYAOWUJUTOUSAINUOFEIXUANBUTUICHUZHELIANGGELINGYUDEYANFA。

ZHONGSHUTUIXINGXINGJIBINGYIAD、PDWEIZHU,QIZHONGADTOURENZUIDA、DANSUNSHANGYEZUICANZHONG。NUOHUA/ANJIN、BAIJIAN/WEICAIJINNIANXIANHOUZHONGZHILEBACEYIZHIJICNP520、elenbecestatDEKAIFA,JIYINTAIKE/AC ImmuneZEZHONGZHILEFENZHUANGDANBAIKANGTIcrenezumabDELIANGGESANQILINCHUANG。SUIRANBAIJIAN/WEICAIZAIFENXILEEmerge、EngageZHIHOUZHUNBEIDIJIAOFENZHUANGDANBAIKANGTIaducanumab,DANZAODAOYEJIEYIPIANZHIYISHENG。ZHONGSHUYAOWUZAIDUONIANMEIYOUJINZHANHOU2019NIANFASHENGLEJIGEZHONGYAOSHIJIAN。YANGSENZHIYAOS-LVANTONGBIQIANGPENWUZHIJISpravatoZAIZHONGZHENGYIYU、SageDEBIEYUNXICHUNTONGJINGMODIZHUZHIJIZulressoZAICHANHOUYIYUDESHANGSHIDOUSHIZHONGYAOLICHENGBEI。DANZHEGELINGYUGENGDUODESHITIAOZHANHEZULI,SageDEKOUFUHUANDAICHANPINSage-217ZAIZHONGZHENGYIYUSANQILINCHUANGSHIBAI,AIERJIANDEGAILIANGSpravatoKANGYIYUYAOWUZESHIBAISANGESANQILINCHUANG。

QITAMANXINGBINGYAOWUYEMIANLINLEISIQINGKUANG,ANJIN/UCBDEYINGPIDANBAIKANGTIromosozumabSUIRANPIZHUNSHANGSHI、DANSHIYINGZHENGBURUYUANLAIYUCEDEKUAN,ANJINHOUXUANBUTUICHUCNSYANFA。HUIRUI/LILAIYUANLAIGAODUKANHAODEZHITONGYAONGFKANGTIYINWEIANQUANWENTIZHIYOUYIGELIAOXIAOYIBANDEJILIANGKENENGHUOPI、DADAYINGXIANGSHANGYEBIAOXIAN。NASHSUIRANREHUOCHAOTIANDANZHENZHENGYOUSHANGYEQIANLIDEMUQIANKANZHIYOUJIAZHUANGXIANSUSHOUTIJIDONGJI。ICPTDEFXRJIDONGJIAOBEIDANSUAN(Ocaliva)SUIRANCHENGWEIDIYIGESANQILINCHUANGCHENGGONGDENASHYAOWU,DANFUZUOYONGXIANZHILEQISHANGYEQIANJING。JILIDEDEASK1YIZHIJIselonsertibZESHIBAILIANGGESANQIHEJIGEZUHELIAOFAERQILINCHUANGSHIYAN,TUICHUNASHYEBULINGRENYIWAI。

2.2. 罕見病

HANJIANBINGYAOWUYINJILIQINGCHU、BIAOZHUNLIAOFAQIANQUE、DUFUZUOYONGNAISHOUCHENGDUJIAOGAO、ZHIFUBUMENYIJIESHOUDENGYUANYINCHENGWEIXIANZAIDAXIAOZHIYAOQIYEQUZHIRUOMUDELINGYU。JIYINLIAOFA、RNALIAOFA、PROTAC、CAR-TDENGRURIZHONGTIANDEJISHUJUNZHIXIANGZHEYIDALEIJIBING,JINNIANZUIDAJINZHANSHIHESUANYAOWUDEZHULIUHUA。DUOJIAJIYINLIAOFABEIGAODIAOSHOUGOU,YISHIJIANLUOYANGZHIGUI、KESHOUGOUDEJIYINLIAOFAGONGSIMINGXIANBUGOUYONGLE。FDAPIZHUNLEDIERGERNAiYAOWUGivosiran、inclisiranZEYOUWANGQUDAIPCSK9KANGTIZHEYICENGJINGGAODUKANHAODEYAOWU,JIHUSUOYOURNAiSHENGWUJISHUQIYEYEDOUYUDAYAOCHANGJIANLILEHEZUOGUANXI。JIYINBIANJICHANPINJINRULINCHUANG,SUIRANDAYAOCHANGBUJUSHANGZAIZAOQI、DANFUTAIDENGQIYEYIJINGKAISHIQIANGGOU。mRNAYAOWUYEQIANHUWANHUANSHICHULAI,ZHONGYUGONGBULEYIXIEZAOQILINCHUANGSHUJU、BAOKUOmRNAKANGTI。DANGRANZHEXIEJISHUHUANZAIZAOQI、BIRANHUIYUDAOYIXIEbug,ZolgensmaJINNIANMAFANSHIBUSHAO。ZHEXIEXINJISHUYEMIANLINCHUANTONGXIAOFENZIYAOWUDEWEIXIE,JINNIANFDAPIZHUNHUIRUIXIAOFENZIATTRYAOWUtafamidisHEGBTDEXIAOFENZILIANDAOXIBAOJIBINGYAOWUOxbryta,LUOSHI XIAOFENZIYAOWUrisdiplamZAISMAYEXIANSHIYUHESUANYAOWULEISILIAOXIAO。

ZHONGLIUYINWEIJICHUYANJIUTOURUHENDASUOYIXIANZAIBEIFENGECHENGDALIANGHANJIANBING。ZHONGLIULINGYUJINNIANZUIZHONGYAODEJINZHANSHIKRASYIZHIJIDESHANLIANGDENGCHANG。KRASSHIZUICHANGJIANDEBIANYIZHIAIJIYIN、BEIZHIYAOJIEXUANSHANGYIJIU,DANCHENGYAOXINGCHA。JINNIANZHONGYUYOULETUPO,AMG510HEMRTX849LIANGGEZHENDUIG12CBIANYIDEYAOWUDOUBAODAOBUCUODEZAOQILINCHUANGSHUJU。LINGYIGEZHONGYAOBADIANSHIBTK,BAIJISHENZHOUSHANGSHILEDIYIKUANZHONGGUOQIYEDULIYANFADEBTKYIZHIJIZANBUTINI。LILAI、MOSHADONGDENGJUTOUZEKAISHIBUJUYIDAIBTKYIZHIJINAIYAOHOUSHICHANG,MOSHADONG27YISHOUGOULEKENIBTKLINGXIANDEArQule、LILAIZEMAILELoxo。JINNIANSHOUKUANXPO-1YIZHIJIXPOVIOTMSHANGSHI,SUIRANDUXINGBUXIAODANBIJINGSHIGEMOXIANXUANZE。LAOPAIZHONGBANGYAOWURUPD-1、PARP、CDK4/6SUIRANYEZAIKUODASHIYINGZHENGHUOJILEISHENGCUNYOUSHISHUJU、DANDIANFUXINGJINZHANYOUXIAN,GENGDUODESHIMOMODISHUQIAN。

秒速赛车控制器PROTACJINNIANYOULIANGGELAOBADIANCHANPINJINRUZHONGLIULINCHUANG,ZHUYAOSHIYANZHENGZHEGEJISHUPINGTAI。CAR-TZEHUIGUIXIANSHI,CHULEJIGEXUEYEZHONGLIUKANGYUANWAIJINZHANYOUXIAN。CAR-TYEMIANLINADCDEWEIXIE,YUQISHUOZHEGEJISHUPINGTAIJUYOUDIANFUXINGBURUSHUOCD19、BCMASHINANDEDENAIJIDABADIAN。LINGWAICAR-TDESHENGCHANWENTIDAOXIANZAIYEMEIYOUCHEDIJIEJUE,LINCHUANGSHIYANHUANZHETUIZULVTAIGAOKUADAYINGDALVYESHOUDAOZHIYI。HER2SIHUSHISHITILIUZHONGZUIJIEJINCD19DEZHONGLIUKANGYUAN,SANGONGDEDS8201YIGAOZAIYAOLIANG、GAOJUBUDUXING、GAOMIANYIJIHUOLIZAIYANZHONGNAIYAORENQUNCHANSHENGJIN100%JIBINGWENDINGLV,BEIASILIEKANG70YISHOUGOUBUFENQUANYI、YOUTIQIAN4GEYUEBEIFDAPIZHUN。FcGAILIANGDEmargetuximab、HER2SHUANGKANGZ25YEZAIBUTONGFANGMIANCHAOGUOYIYOUHER2YAOWU。

QITAHANJIANBINGZHUYAOJINZHANBAOKUONANGZHONGXINGFEIXIANWEIHUA(CF)SANYAOZUHETrikaftaSHANGSHI,LING90%YISHANGCFHUANZHEYOULEZHILIAOYAOWU。ReataDENrf2JIHUOJIOmaveloxoloneZAIDUOGEROSXIANGGUANHANJIANBINGXIANSHIZHUCESHUIPINGLIAOXIAO,JIASHENYEJIEDUICHENGYAOXINGDELIJIE。XINJIDEJAK2YIZHIJIfedratinibSHANGSHIYONGYUGUSUIXIANWEIHUA,YANYILANGZIHUITOU。HANJIANBINGDEJIXIANSHIDANLIHUANZHE,RNAYAOWUmilasenZHUANMENWEIYIWEIJIAOZUOMilaDEXIAOHUANZHELIANGSHENDINGZUO。ZHEGEMOSHISUIRANHUANBUSHIZHULIU,DANZHENDUIQINGCHUJILIDEJINGZHUNYIXUEQUESHIDAIBIAOWEILAI、GUANGPUKANGAIYAOZAIMOUXIERENYANZHONGYIJINGSHIGEZIXIANGMAODUNDETIFA。

3. 社會責任

GENJUXIANZAIDEJISHUSHUIPINGXINYAOYINGGAISHISUOYOUSHECHIPINZHONGZUISHECHIDECHANPIN、ZHAODAOYOUZHIXINYAONANDUYUANGAOYUZHAODAOJIPINZHANSHI,DANYINYAOPINDUTEGONGNENG、KEJIXINGSHIGEBIXUJIEJUEDEWENTI。AIMASHIDINGJIAGAOYU99%RENKOUCHENGSHOUNENGLIWURENZHIYI,DANKeytrudaBUXING。LONGDUANSHIJIAGEBAOZHENG,JINNIANJIGEBINGGOUSHOUDAOFTCDEYANGESHENCHA。XINJIBEIPOPAIMAIYINXIEBINGYAOWUOtezla,LUOSHISHOUGOUSparkBEIYANCHI10GEYUE。YAOPINHEFALONGDUANXUYAOZHUANLIXITONGDEZHICHI,DANZHUANLIGUOQIHOUYINGGAIYUNXUFANGZHIYAODEKUAISUJINRUYIHUANJIEZHIFUYALI。YIHANDESHISUIRANKANGTIYAOWUYIJINGSHIYAOPINZHIFUDEDATOU,DANSHENGWULEISIYAODEJIANGUANBINGWEIYUSHIJUJIN、MEIGUOSHICHANGSHENGWULEISIYAOSHENTOULVBUJINRENYI。APIANLEIZHITONGYAOLANYONGSUIRANYUANYINFUZADANZHIYAOYEYENANTUOGANXI,PUDUYAOCHANGJINNIANBEIFA120YIPOCHAN、QIANGSHENGYEBEIPANFAJINSHUYI。MOSHADONGWEIFEIZHOUDIQUJIHUMIANFEIKAIFADEAIBOLAYIMIAOSHANGSHISHIGENANDELIANGDIAN。

秒速赛车控制器QIAOZHI•MOKE1950NIANZAIFUJINIYAYIXUEYUANJIANGYANDENEIDUANMINGYAN“YAOWUBUSHIWEILELIRUN、ERSHIWEILEHUANZHE”GUOQU70NIANCHENGWEIZHIYAOGONGYEDEZUIGAOLIXIANG。DANRENHEXINGYESHENGCUNBIXUYOUZUGOULIRUN,ZHEDUANHUAGENGYINGGAISHIYIGEYAOCHANGHUOQULIRUNFANGSHIERBUSHISHENGCUNFANGSHIDEZHINAN。MOKEBINGMEIYOUSHUOLIRUNBUZHONGYAO,ZHISHISHUOHUOQULIRUNDEZUIJIALUJINGBUSHIZHIJIEDINGZHULIRUN、ERSHISHOUXIANYAOKAOLVNENGWEIHUANZHEDAILAISHENMESHOUYI。ZAIZHEGEJIANGYANZHONGTAHUANTIDAOYAOPINKEJIXINGWENTI,SHUOWOMENZAIZHAODAOSUOYOURENDOUNENGFUDANDEQIDEZUIHAOYAOWUQIANBUNENGTINGZHINULI。70NIANGUOQULE,YAOPINJIAZHIHEKEJIXINGWENTIRENGRANSHIJUEDINGZHIYAOGONGYEDASHIXIAOQINGDEHEXINQUDONGLI。

4. 小結

XIANSHIYULIXIANGZONGHUIYOUYIDINGCHAJU,FOUZELIXIANGYEJIUSHIQUCUNZAIDEJIAZHI。YUEYOUYINQINGYUANQUE,DANZHIYAOYEZHULIUSHIJIJIDE。XIANZAIDUOSHUXINYAOXIANSHIMINGQUEZHILIAOJIAZHI,HENDUOGAIBIANJIBINGJINCHENGERBUJINJINKONGZHIZHENGZHUANG。XINJISHULINGYIQIANGENBENWUFAXIANGXIANGDELIAOXIAOCHENGWEIXIANSHI,RUWANQIFEIAIHUANZHECHANGQISHENGCUN、SHIMINGERTONGKANJIANCAIHONG、XUEYOUBINGHUANZHEGAOBIECHUXUE。JINGUANKEJIXINGSHIGEWENTI,DANSHEHUIZONGTIDUIYIYAOCHUANGXINSHIRENTONGDE。FDAJINGCHANGTIQIANSHUYUEPIZHUNJIXUYAOWU,ZIBENYEZAIGAOQIANGDUZHICHIGAOFENGXIANJISHUDEKAIFA。ZUOWEIXINYAOYANFAYIYUANWOYEKEYIZUOZHENGKEXUEJIAMENZAIFEICHANGNULIDIXUNZHAOXIAYIGEKeytruda,ZHISHISHENGMINGGUOCHENGFUZACHENGDUCHAOGUODUOSHURENDEXIANGXIANG。FDAJINNIANPIZHUNLE45GEXINYAO,SUIRANBURUQUNIANDUODANYEYUANCHAOLISHIPINGJUNSHUIPING。ZHESHUOMINGHUANZHE、ZHIFU、YAOJIA、ZIBEN、YAOCHANGDENGDUOFANGGUANXIXIANGDUIHEXIE,XINYAOSHENGTAIXITONGJIANKANGQINGKUANGLIANGHAO。DANGRANZHIYAOYEYEYOUZHUDUOXUYAOGAIJINDEDIFANG,ZHEZHENGSHI2020NIANJIUYAODAOLAIDEYUANYIN。

YUANBIAOTI:YUANCHUANG | RANGYIBUFENHUANZHEXIANJIANKANGQILAI:YAOYUANHUIGU2019