秒速赛车控制器

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2020年將在美國上市的十大藥物
發布時間: 2019-12-24     來源: 新浪醫藥

BIANYISHUnewborn

QUANQIUZHIMINGSHENGMINGKEXUEXINGYESHICHANGZIXUNGONGSIEvaluateQIXIAEP VantageJINRIFABUBAOGAO,DUI2020NIANJIANGZAIMEIGUOSHANGSHIDEYAOWUJINXINGLEFENXI。BAOGAOZHICHU,YOUYUFDADEXUNSUPIZHUN,YOUJIKUANYUANBENYUQIZAI2020NIANSHANGSHIDEZHONGBANGCHANPIN,SHANGSHISHIJIANBEITIQIANDAOLE2019NIAN,BAOKUOVertexDENANGXINGXIANWEIHUAYAOWUTrikafta,GAIYAOTIJIAOSHENQINGHOUSANGEYUEJIUHUODELEPIZHUN,BIPDUFAMUBIAORIQITIQIANLE5GEYUE。GBTLIANZHUANGXIBAOBING(SCD)ZHILIAOYAOWUOxbrytaYETIQIANSANGEYUEHUOPI。

JUMAIFANGFENXISHIYUJI,TrikaftaZAI2024NIANDEXIAOSHOUEJIANGJIEJIN40YIMEIYUAN;GENJUEvaluatePharmaDESHUJU,OxbrytaZAI2024NIANDEXIAOSHOUEJIANGDA16YIMEIYUAN。ZAIOxbrytaHUOPIDEQIANJIZHOU,NUOHUADESCDYAOWUAdakveoYEHUODELEFDAPIZHUN,YONGYUJIANGDISCDHUANZHEXUEGUANZUSAIXINGWEIXIANGDEFASHENGPINLV,SHISHOUGEYESHIWEIYIYIGETONGGUOJIEHEPXUANZESUFAHUIZHILIAOZUOYONGDEBAXIANGSHENGWUZHIJI。YINCI,SCDJIANGSHITOUZIZHEZAI2020NIANGUANZHUDEYIDAJIAODIAN。

秒速赛车控制器BAOGAOHUANTEBIETIDAOLEBAIJISHENZHOUDEKANGPD-1LIAOFAtislelizumab,YOUYUYUBMSDEOpdivoZHONGDIE,XINJITUICHUHEZUO,BAIJISHENZHOUSHOUHUILEtislelizumabDEQUANQIUSHOUQUAN。BAOGAOZHICHU,SUIRANtislelizumabZAIQUANQIUQITASHICHANGDEQIANJINGKENENGHENDI,DANZAIZHONGGUO,GAIYAOYUJIZAI2024NIANJIANGCHENGWEIZHONGBANGCHANPIN。

JIYUEvaluatePharmaDEGONGSHIYIJIMAIFANGFENXISHIYUCE,2020NIANJIANGZAIMEIGUOSHANGSHIDETOP10CHANPINRUXIA:

1、trastuzumab deruxtecan

秒速赛车控制器GAIYAOYU12YUE20RIHUODEFDAJIASUPIZHUN,PINPAIMINGWEIEnhertu,YONGYUZHILIAOZAIZHUANYIXINGJIBINGZHONGYIJIESHOUGUO2ZHONGHUO2ZHONGYISHANGKANGHER2YAOWUZHILIAODEHER2YANGXINGZHUANYIXINGRUXIANAICHENGRENHUANZHE。CICIPIZHUNJIAOPDUFAMUBIAORIQI2020NIANDIERJIDUDAFUTIQIAN。LAIZIGUANJIANIIQIYANJIUDESHUJUXIANSHI,EnhertuZAINANZHIXINGHER2YANGXINGHUANZHEZHONGDEZONGHUANJIELVWEI60.9%。

GAIYAOYOUASILIKANGYUDIYISANGONGHEZUOKAIFA,SHIYIZHONGXINYIDAIKANGTIADCYAOWU,TONGGUOYIZHONG4TAILIANJIEZIJIANGBAXIANGHER2DERENYUANHUADANKELONGKANGTItrastuzumabYUYIZHONGXINXINGTUOPUYIGOUMEI1YIZHIJIexatecanYANSHENGWULIANJIEZAIYIQI,KEBAXIANGDISONGXIBAODUZHIJIZHIAIXIBAONEI,YUTONGCHANGDEHUALIAOXIANGBI,KEJIANSHAOXIBAODUZHIJIDEQUANSHENBAOLU。

2、Palforzia

GAIYAOSHIAimmune TherapeuticsJIYUZHUANYOUDEKOUFUTUOMINMIANYILIAOFA(CODIT)ZHILIAOPINGTAIKAIFADEYIKUANKOUFUSHENGWUMIANYILIAOFA,YONGYUDUIHUASHENGGUOMINDE4-17SUIERTONGHEQINGSHAONIAN,JIANGDIYIWAISHERUHUASHENGHOUGUOMINFANYINGDEFASHENGLVHEYANZHONGCHENGDU。JINNIAN9YUE,PalforziaHUODELEFDAGUOMINCHANPINZIXUNWEIYUANHUITUIJIANPIZHUNDESHENCHAYIJIAN,PDUFAMUBIAORIQIWEI2020NIAN1YUE。

HUASHENGGUOMINSHIZUICHANGJIANDESHIWUGUOMINZHIYI,MUQIANSHANGWUPIZHUNDELIAOFA,QIBIAOZHUNHULIYIZHISHIYANGEDEPAICHUYINSHIYIJIZAIYIWAISHERUYINQIGUOMINFANYINGSHIJISHIGEIYUJIUYUANYAOWU。RUGUOHUODEPIZHUN,PalforziaJIANGCHENGWEIDIYIKUANYONGYUHUASHENGGUOMINDELIAOFA。

3、Ozanimod

秒速赛车控制器GAIYAOSHIXINJIZAI2015NIANYI73YIMEIYUANSHOUGOUReceptosDEHEXINZICHAN,YONGYUZHILIAOFUFAXINGDUOFAXINGYINGHUAZHENG(RMS),ZHENGZAIJIESHOUMEIGUOHEOUMENGJIANGUANJIGOUDESHENCHA。GAIYAOSHIYIKUANKOUFU1-LINSUANQIAOANCHUN(S1P)SHOUTIDIAOJIEJI,NENGGOUYIGAOQINHELIXUANZEXINGJIEHES1PYAXING1(S1P1)HEYAXING5(S1P5),MUQIANZHENGKAIFAYONGYUDUOZHONGMIANYIYANZHENGSHIYINGZHENG。

OzanimodYUNUOHUADERMSXINYAOMayzentJUYOUXIANGTONGDEZUOYONGJIZHI,HOUZHEYIYUJINNIAN3YUEHUOFDAPIZHUN。

4、Inclisiran

GAIYAOSHIYOUTMCGONGSIKAIFADEYIZHONGJIANGDANGUCHUNYAOWU,TONGGUOPIXIAZHUSHEGEIYAO,MEINIANZHIXUZHUSHE2CI。ZHESHIYIZHONGKAICHUANGXINGDE、YIPCSK9WEIBADIANDERNAiYAOWU,ZAIIIIQILINCHUANGZHONG,YUANWEIJIXIANGBIXIANZHUJIANGDILELDL-CSHUIPING。

PCSK9SHIJINNIANLAIJIANGDANGUCHUNLINGYUDEYIGEXINBADIAN,TIGONGLEYIZHONGQUANXINDEZHILIAOMOSHILAIDUIKANGLDL-C,BEISHIWEITATINGLEIZHIHOUJIANGDANGUCHUNLINGYUQUDEDEZUIDAJINBU。JINNIAN11YUE,NUOHUAXUANBUYI94YIMEIYUANSHOUGOUTMCGONGSI,JIANGinclisiranSHOURUNANGZHONG。

5、Roxadustat

秒速赛车控制器GAIYAOYOUFibroGenFAXIAN、YUASILIKANGHEANSITAILAILIANHEKAIFA,ZHESHIYIZHONGKOUFUXIAOFENZIDIYANGYOUDAOYINZIFUANXIANQIANHUAMEI(HIF-PH)YIZHIJI,KAIFAYONGYUSHENXINGPINXUEDEZHILIAO。2018NIAN12YUE,roxadustatLVXIANZAIZHONGGUOHUOPI,ZHILIAOMANXINGSHENZANGBINGTOUXIHUANZHEDEPINXUE,JINNIAN8YUEZAICIHUOPIXINSHIYINGZHENG,YONGYUZHILIAOFEITOUXIYILAIMANXINGSHENZANGBINGHUANZHEDEPINXUE。

秒速赛车控制器GAIYAOSHIQUANQIUHUOPIDESHOUGEHIF-PHYIZHIJILEIPINXUEYAOWU。DIYANGYOUDAOYINZIDESHENGLIZUOYONGBUJINSHIHONGXIBAOSHENGCHENGSUBIAODAZENGJIA,YENENGSHIHONGXIBAOSHENGCHENGSUSHOUTIYIJICUJINTIEXISHOUHEXUNHUANDEDANBAIBIAODAZENGJIA。RoxadustatTONGGUOMONIFUANXIANQIANHUAMEI(PH)DEDIWUZHIYITONGWUERSUANLAIYIZHIPHMEI,YINGXIANGPHMEIZAIWEICHIHIFSHENGCHENGHEJIANGJIESULVPINGHENGFANGMIANDEZUOYONG,CONGERDADAOJIUZHENGPINXUEDEMUDE。

6、Sacituzumab govitecan

秒速赛车控制器GAIYAOYOUImmunomedicsKAIFA,YONGYUXIANQIANYIJIESHOUGUOZHISHAO2ZHONGLIAOFAZHILIAOZHUANYIXINGJIBINGDEZHUANYIXINGSANYINXINGRUXIANAI(mTNBC)HUANZHE。JINNIAN1YUE,GAIYAOYINZHIZAOWENTIBEIFDAJUJUEPIZHUN。12YUECHU,GAIGONGSIZHONGXINXIANGFDATIJIAOLESHENQING。RUGUOHUOPI,GAIYAOJIANGCHENGWEISHOUGEZHILIAOmTNBCDEADCYAOWU。ZAIIIIQILINCHUANGZHONG,GAIYAOZHILIAODEZONGHUANJIELVWEI34%。

GAIYAOSHIYIZHONGXINXINGADCYAOWU,YOUBAXIANGTROP-2KANGYUANDERENYUANHUAIgG1KANGTIYUHUALIAOYAOWUYILITIKANGDEDAIXIEHUOXINGCHANWUSN-38OULIANERCHENG。TNBCSHIYIZHONGZHILIAOXUANZEFEICHANGYOUXIANDERUXIANAILEIXING,JINNIAN3YUE,LUOSHITecentriqLIANHEHUALIAOHUOPIYIXIANZHILIAOPD-L1YANGXINGTNBC,CHENGWEIZHILIAOGAIJIBINGDESHOUGEAIZHENGMIANYIZHILIAOFANGAN。

7、Filgotinib

GAIYAOSHIJILIDEYUGalapagosHEZUOKAIFADEYIKUANKOUFUJAK1YIZHIJI,YUSHANGZHOUXIANGFDATIJIAOLEZHILIAOLEIFENGSHIXINGGUANJIEYAN(RA)DEXINYAOSHENQING。JILIDETONGSHITIJIAOLEYIZHANGYOUXIANSHENPINGQUAN,LAISUODUANSHENCHASHIJIAN。YANZHENGXINGJIBINGSHIJIBINGGANHEHIVZHIHOU,JILIDEDEYIGEXINDEZENGCHANGDIAN。

CHULERAZHIWAI,SHUANGFANGMUQIANYEZHENGZAIKAIFAfilgotinibYONGYUQITAYANZHENGXINGJIBING。RUGUOSHANGSHI,filgotinibJIANGYUBAOKUOHUIRUIXeljanz、LILAIOlumiant、AIBOWEIRinvoqZAINEIDEDUOKUANJAKYIZHIJIZHANKAIJINGZHENG。ZHIDEYITIDESHI,AIBOWEIZAIRinvoqSHENCHAFANGMIAN,YETIJIAOLEYIZHANGYOUXIANSHENPINGQUANLAIJIASUMEIGUOFANGMIANDEJIANGUANSHENCHA,ZUIJINGAIYAOYEHUODELEOUMENGPIZHUN。

8、Valoctocogene roxaparvovec

GAIYAOSHIYOUBioMarinYANFADEYIKUANJIYUXIANXIANGGUANBINGDU(AAV)DEJIYINLIAOFA,YONGYUZHILIAOAXINGXUEYOUBING,JINNIAN11YUEZAIOUMENGTIJIAOLESHANGSHISHENQING,ZHEYESHIZHENDUIRENHELEIXINGXUEYOUBINGJIYINZHILIAOTIJIAODESHOUFENSHENQING。

秒速赛车控制器GAIYAOTONGGUOXIANGHUANZHETINEIDISONGNINGXUEYINZIVIIIGONGNENGJIYIN,HUIFUVIIIDECHANSHENG,CONGERXIAOCHUHUOJIANSHAOJINGMOVIIISHUZHUXUQIU。ZAIIIIQILINCHUANGZHONG,GAIYAODANCIZHUSHEGEIYAOSANNIANHOU,HUANZHENIANHUACHUXUELVJIANGDI96%,MUBIAOGUANJIECHUXUE100%XIAOCHU,NIANHUAYINZIVIIISHIYONGJIANGDI96%。CIWAI,SUOYOUHUANZHEJIXUBAOCHIWUXUYINZIVIIIYUFANGXINGZHILIAO,TINEIYINZIVIIIBIAODAJINRUPINGWENQI,BIAOMINGKENENGSHIXIANCHIJIUDE、CHANGQIDEBIAODA。

9、Rimegepant

GAIYAOYOUBiohavenKAIFA,SHIYIZHONGKOUFUJIANGGAISUJIYINXIANGGUANTAI(CGRP)JIEKANGJI,ZHENGKAIFAYONGYUPIANTOUTONGHENANZHIXINGSANCHASHENJINGTONGDEZHILIAO。ZAIZHILIAOJIXINGPIANTOUTONGDEGUANJIANIIIQILINCHUANGZHONG,YUANWEIJIXIANGBI,DANJILIANGrimegepantKOUQIANGBENGJIEPIANZHILIAODEHUANZHEJINGLILEKUAISUHECHIJIUDELINCHUANGHUOYI,FUYAOHOU2XIAOSHIXUNSUYOUXIAODIHUANJIETENGTONGJIPIANTOUTONGXIANGGUANZHENGZHUANG。

秒速赛车控制器CGRPJIQISHOUTIZAIYUPIANTOUTONGBINGLISHENGLIXUEXIANGGUANDESHENJINGXITONGQUYUBIAODA,SHIPIANTOUTONGYAOWUYANFADEREMENBADIAN。JIEZHIMUQIAN,YIYOU3KUANBAXIANGCGRPJIQISHOUTIDEDANKELONGPIANTOUTONGYAOWUSHANGSHI。CHULErimegepant,AIERJIANDEKOUFUCGRPSHOUTIJIEKANGJIubrogepantYONGYUPIANTOUTONGJIXINGZHILIAODESHENQINGYEZHENGZAIJIESHOUFDASHENCHA。

10、Risdiplam

GAIYAOSHIYOULUOSHIKAIFADEYIKUANZHILIAOJISUIXINGJIWEISUOZHENG(SMA)DEYAOWU。ZHESHIYIZHONGKOUFUYETI、YUNDONGSHENJINGYUANCUNHUOJIYIN2(SMN2)JIANJIEXIUSHIJI,ZHIZAICHIXUZENGJIAHEWEICHIZHONGSHUSHENJINGXITONGHEWAIZHOUZUZHIZHONGDESMNDANBAISHUIPING。RisdiplamKOUFUGEIYAOHOUCHENGXIANQUANSHENFENBU,KECHIXUZENGJIAZHONGSHUSHENJINGXITONGHEWAIZHOUZUZHISMNDANBAISHUIPING,YIXIANSHICHUGAISHAN1XING、2XING、3XINGSMAHUANZHEDEYUNDONGGONGNENG。

秒速赛车控制器RUGUOHUOPI,risdiplamJIANGCHENGWEIZHILIAOSUOYOULEIXINGSMADESHOUGEKOUFUYAOWU。MUQIAN,SMALINGYUYIYOU2KUANYAOWUSHANGSHI,YIKUANSHIBOJIAN/IonisDESpinraza,ZHESHIYIZHONGFANYIGUAHEGANSUAN,TONGGUOQIAONEIZHUSHE,XUYAODINGQIGEIYAO;LINGYIKUANSHINUOHUADEZolgensma,ZHESHIYIZHONGQIANZAIDEYICIXINGJIYINLIAOFA,DINGJIAGAODA210WANMEIYUAN。ZUIJIN,NUOHUAXUANBUZAIMEIGUOYIWAIDIQUKAIZHANZolgensmaZENGYAOHUODONG,CAIYONG“CHOUJIANG”XINGSHI,MEINIANZENGYAO100JI。

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